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A novel alkaloid from the fruiting bodies of Ganoderma sinense Zhao,Xu et Zhang

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【Author】 Chao Liu,Fen Zhao,RuoYun Chen~* Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education,Beijing 100050,China

【摘要】 <正>A new alkaloid,sinensine(1),had been isolated from the fruiting bodies of Ganoderma sinense Zhao,Xu et Zhang.Its structure was elucidated on the basis of 1D and 2D spectral analysis.This alkaloid exhibited activity in protecting the injury induced by hydrogen peroxide oxidation on HUVEC,with EC50 value 6.2μmol/L.

【Abstract】 A new alkaloid,sinensine(1),had been isolated from the fruiting bodies of Ganoderma sinense Zhao,Xu et Zhang.Its structure was elucidated on the basis of 1D and 2D spectral analysis.This alkaloid exhibited activity in protecting the injury induced by hydrogen peroxide oxidation on HUVEC,with EC50 value 6.2μmol/L.

【关键词】 AlkaloidGanoderma sinenseSinensine
【Key words】 AlkaloidGanoderma sinenseSinensine
【基金】 supported by the Ministry of Science and Technology of the People’s Republic of China (No.2007Fy130100)
  • 【文献出处】 Chinese Chemical Letters ,中国化学快报(英文版) , 编辑部邮箱 ,2010年02期
  • 【分类号】R284.1
  • 【下载频次】121
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